九州大学大学院医学研究院
衛生・公衆衛生学分野

Natriuretic Peptides Studies Collaboration (Ninomiya T)

Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis.

Lancet Diabetes Endocrinol　4: 840-849, 2016

Woodward M, Hirakawa Y, Kengne AP, Matthews DR, Zoungas S, Patel A, Poulter N, Grobbee R, Cooper M, Jardine M, Chalmers J; ADVANCE Collaborative Group

Prediction of 10-year vascular risk in patients with diabetes: the AD-ON risk score.

Diabetes Obes Metab 　18: 289-294, 2016

Mohammedi K, Woodward M, Hirakawa Y, Zoungas S, Colagiuri S, Hamet P, Harrap S, Poulter N, Matthews DR, Marre M, Chalmers J

Presentations of major peripheral arterial disease and risk of major outcomes in patients with type 2 diabetes: results from the ADVANCE-ON study.

Cardiovasc Diabetol　15: 129, 2016

Mohammedi K, Woodward M, Hirakawa Y, Zoungas S, Colagiuri S, Hamet P, Harrap S, Poulter N, Matthews DR, Marre M, Chalmers J

Microvascular and macrovascular disease and risk for major peripheral arterial disease in patients with type 2 diabetes.

Diabetes Care　39: 1796-1803, 2016

Yu S, Arima H, Bertmar C, Hirakawa Y, Priglinger M, Evans K, Krause M

Depression but not anxiety predicts recurrent cerebrovascular events.

Acta Neurol Scand　134: 29-34, 2016

Ikeda F, Shikata K, Hata J, Fukuhara M, Hirakawa Y, Ohara T, Mukai N, Nagata M, Yoshida D, Yonemoto K, Esaki M, Kitazono T, Kiyohara Y, Ninomiya T

Combination of Helicobacter pylori Antibody and Serum Pepsinogen as a Good Predictive Tool of Gastric Cancer Incidence: 20-Year Prospective Data From the Hisayama Study.

J Epidemiol 　26: 629-636, 2016

Tsukuya G, Samukawa T, Matsumoto K, Fukuyama S, Kumamoto T, Uchida A, Koriyama C, Ninomiya T, Inoue H

Comparison of the COPD Population Screener and International Primary Care Airway Group questionnaires in a general Japanese population: the Hisayama study.

Int J Chron Obstruct Pulmon Dis 　 11: 1903-1909, 2016

Liyanage T, Ninomiya T, Wang A, Neal B, Jun M, Wong MG, Jardine M, Hillis GS, Perkovic V

Effects of the Mediterranean Diet on Cardiovascular Outcomes-A Systematic Review and Meta-Analysis.

PLoS One 　11: e0159252, 2016

Hamasaki H, Honda H, Okamoto T, Koyama S, Suzuki SO, Ohara T, Ninomiya T, Kiyohara Y, Iwaki T

Recent increases in hippocampal tau pathology in the aging Japanese population: the Hisayama Study.

J Alzheimers Dis 　55: 613-624, 2016

Torisu K, Zhang X, Nonaka M, Kaji T, Tsuchimoto D, Kajitani K, Sakumi K, Torisu T, Chida K, Sueishi K, Kubo M, Hata J, Kitazono T, Kiyohara Y, Nakabeppu Y

PKCη deficiency improves lipid metabolism and atherosclerosis in apolipoprotein E-deficient mice.

Genes Cells 　21: 1030-1048, 2016

Hirabayashi N, Hata J, Ohara T, Mukai N, Nagata M, Shibata M, Gotoh S, Furuta Y, Yamashita F, Yoshihara K, Kitazono T, Sudo N, Kiyohara Y, Ninomiya T

Association between diabetes and hippocampal atrophy in elderly Japanese: the Hisayama Study.

Diabetes Care　 39: 1543-1549, 2016

Qiu M, Sato S, Zheng D, Wang X, Carcel C, Hirakawa Y, Sandset EC, Delcourt C, Arima H, Wang J, Chalmers J, Anderson CS; INTERACT Investigators

Admission heart rate predicts poor outcomes in acute intracerebral hemorrhage: the intensive blood pressure reduction in acute cerebral hemorrhage trial studies.

Stroke 　47: 1479-1485, 2016

Hirakawa Y, Arima H, Webster R, Zoungas S, Li Q, Harrap S, Lisheng L, Hamet P, Mancia G, Poulter N, Neal B, Williams B, Rogers A, Woodward M, Chalmers J

Risks associated with permanent discontinuation of blood pressure-lowering medications in patients with type 2 diabetes.

J Hypertens 　34: 781-787, 2016

Tanaka S, Ninomiya T, Taniguchi M, Fujisaki K, Tokumoto M, Hirakata H, Ooboshi H, Kitazono T, Tsuruya K

Comparison of oral versus intravenous vitamin D receptor activator in reducing infection-related mortality in hemodialysis patients: the Q-Cohort Study.

Nephrol Dial Transplant　 31: 1152-1160, 2016

NCD Risk Factor Collaboration (NCD-RisC) (Hata J, Ninomiya T)

Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants.

Lancet　 387: 1513-1530, 2016

Xie X, Liu Y, Perkovic V, Li X, Ninomiya T, Hou W, Zhao N, Liu L, Lv J, Zhang H, Wang H

Renin-angiotensin system inhibitors and kidney and cardiovascular outcomes in patients with CKD: a bayesian network meta-analysis of randomized clinical trials.

Am J Kidney Dis　67: 728-741, 2016

Xie X, Atkins E, Lv J, Bennett A, Neal B, Ninomiya T, Woodward M, MacMahon S, Turnbull F, Hillis GS, Chalmers J, Mant J, Salam A, Rahimi K, Perkovic V, Rodgers A

Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis.

Lancet　387: 435-443, 2016

Shibata M, Ninomiya T, Anno K, Kawata H, Iwaki R, Sawamoto R, Kubo C, Kiyohara Y, Sudo N, Hosoi M

Perceived inadequate care and excessive overprotection during childhood are associated with greater risk of sleep disturbance in adulthood: the Hisayama Study.

BMC Psychiatry　 16: 215, 2016

Sakane N, Sato J, Tsushita K, Tsujii S, Kotani K, Tominaga M, Kawazu S, Sato Y, Usui T, Kamae I, Yoshida T, Kiyohara Y, Sato S, Tsuzaki K, Takahashi K, Kuzuya H; Japan Diabetes Prevention Program (JDPP) Research Group

Effects of lifestyle intervention on weight and metabolic parameters in patients with impaired glucose tolerance related to beta-3 adrenergic receptor gene polymorphism Trp64Arg(C/T): results from the Japan Diabetes Prevention Program.

J Diabetes Investig 　7: 338-342, 2016

NCD Risk Factor Collaboration (NCD-RisC) (Kiyohara Y, Ninomiya T)

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million participants.

Lancet 　387: 1377-1396, 2016

Honda H, Sasaki K, Hamasaki H, Shijo M, Koyama S, Ohara T, Ninomiya T, Kiyohara Y, Suzuki SO, Iwaki T

Trends in autopsy-verified dementia prevalence over 29 years of the Hisayama Study.

Neuropathology 　36: 383-387, 2016

Fuyuno Y, Yamazaki K, Takahashi A, Esaki M, Kawaguchi T, Takazoe M, Matsumoto T, Matsui T, Tanaka H, Motoya S, Suzuki Y, Kiyohara Y, Kitazono T, Kubo M

Genetic characteristics of inflammatory bowel disease in a Japanese population.

J Gastroenterol 　51: 672-681, 2016

Nagai M, Ohkubo T, Miura K, Fujiyoshi A, Okuda N, Hayakawa T, Yoshita K, Arai Y, Nakagawa H, Nakamura K, Miyagawa N, Takashima N, Kadota A, Murakami Y, Nakamura Y, Abbott RD, Okamura T, Okayama A, Ueshima H; NIPPON DATA80 Research Group (Kiyohara Y)

Association of total energy intake with 29-year mortality in the Japanese: NIPPON DATA80.

J Atheroscler Thromb 　23: 339-354, 2016

Hashimoto S, Yasuda M, Ninomiya T, Hata J, Yoshida D, Tahara-Asakuma T, Hirakawa Y, Arakawa S, Fujiwara K, Kiyohara Y, Ishibashi T

Foveal and macular thickness in a Japanese population: the Hisayama Study.

Ophthalmic Epidemiol 　23: 202-208, 2016

Takae K, Nagata M, Hata J, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Tsuruya K, Kitazono T, Kiyohara Y, Ninomiya T

Serum uric acid as a risk factor for chronic kidney disease in a Japanese community - the Hisayama Study -.

Circ J 　80: 1857-1862, 2016

Hata J, Mukai N, Nagata M, Ohara T, Yoshida D, Kishimoto H, Shibata M, Hirakawa Y, Endo M, Ago T, Kitazono T, Oike Y, Kiyohara Y, Ninomiya T

Serum angiopoietin-like protein 2 is a novel risk factor for cardiovascular disease in the community: the Hisayama Study.

Arterioscler Thromb Vasc Biol　 36: 1686-1691, 2016

Okayama A, Okuda N, Miura K, Okamura T, Hayakawa T, Akasaka H, Ohnishi H, Saitoh S, Arai Y, Kiyohara Y, Takashima N, Yoshita K, Fujiyoshi A, Zaid M, Ohkubo T, Ueshima H; NIPPON DATA80 Research Group

Dietary sodium-to-potassium ratio as a risk factor for stroke, cardiovascular disease and all-cause mortality in Japan: the NIPPON DATA80 cohort study.

BMJ Open　 6: e011632, 2016

Fukuyama S, Matsumoto K, Kaneko Y, Kan-O K, Noda N, Tajiri-Asai Y, Nakano T, Ishii Y, Kiyohara Y, Nakanishi Y, Inoue H; Hisayama Pulmonary Physiology Study Group

Prevalence of airflow limitation defined by pre- and post-bronchodilator spirometry in a community-based health checkup: the Hisayama Study.

Tohoku J Exp Med 　238: 179-184, 2016

Shiwa Y, Hachiya T, Furukawa R, Ohmomo H, Ono K, Kudo H, Hata J, Hozawa A, Iwasaki M, Matsuda K, Minegishi N, Satoh M, Tanno K, Yamaji T, Wakai K, Hitomi J, Kiyohara Y, Kubo M, Tanaka H, Tsugane S, Yamamoto M, Sobue K, Shimizu A

Adjustment of cell-type composition minimizes systematic bias in blood DNA methylation profiles derived by DNA collection protocols.

PLoS One 　11: e0147519, 2016

Chatterjee S, Peters SA, Woodward M, Mejia Arango S, Batty GD, Beckett N, Beiser A, Borenstein AR, Crane PK, Haan M, Hassing LB, Hayden KM, Kiyohara Y, Larson EB, Li CY, Ninomiya T, Ohara T, Peters R, Russ TC, Seshadri S, Strand BH, Walker R, Xu W, Huxley RR

Type 2 diabetes as a risk factor for dementia in women compared with men: a pooled analysis of 2.3 million people comprising more than 100,000 cases of dementia.

Diabetes Care 　39: 300-307, 2016

Umemoto S, Ogihara T, Matsuzaki M, Rakugi H, Ohashi Y, Saruta T; Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial Group (Kiyohara Y)

Effects of calcium channel blocker-based combinations on intra-individual blood pressure variability: post hoc analysis of the COPE trial.

Hypertens Res　 39: 46-53, 2016

Kishimoto H, Ohara T, Hata J, Ninomiya T, Yoshida D, Mukai N, Nagata M, Ikeda F, Fukuhara M, Kumagai S, Kanba S, Kitazono T, Kiyohara Y

The long-term association between physical activity and risk of dementia in the community: the Hisayama Study.

Eur J Epidemiol 　31: 267-274, 2016

Takeshita T, Kageyama S, Furuta M, Tsuboi H, Takeuchi K, Shibata Y, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y, Yamashita Y

Bacterial diversity in saliva and oral health-related conditions: the Hisayama Study.

Sci Rep　 6: 22164, 2016