九州大学大学院医学研究院
衛生・公衆衛生学分野

Sumimoto Y, Yanagita M, Miyamatsu N, Okuda N, Nishi N, Nakamura Y, Nakamura K, Miyagawa N, Miyachi M, Kadota A, Ohkubo T, Okamura T, Ueshima H, Okayama A, Miura K; for NIPPON DATA2010 Research Group( Kiyohara Y, Ninomiya T)

Association between socioeconomic status and physical inactivity in a general Japanese population: NIPPON DATA2010.

PLoS One　16: e0254706, 2021

Mizuno Y, Abolhassani N, Mazzei G, Sakumi K, Saito T, Saido TC, Ninomiya T, Iwaki T, Yamasaki R, Kira JI, Nakabeppu Y

MUTYH actively contributes to microglial activation and impaired neurogenesis in the pathogenesis of alzheimer's disease.

Oxid Med Cell Longev　2021: 8635088, 2021

Iso H, Cui R, Takamoto I, Kiyama M, Saito I, Okamura T, Miyamoto Y, Higashiyama A, Kiyohara Y, Ninomiya T, Yamada M, Nakagawa H, Sakurai M, Shimabukuro M, Higa M, Shimamoto K, Saito S, Daimon M, Kayama T, Noda M, Ito S, Yokote K, Ito C, Nakao K, Yamauchi T, Kadowaki T

Risk Classification for Metabolic Syndrome and the Incidence of cardiovascular disease in Japan with low prevalence of obesity: a pooled analysis of 10 prospective cohort studies.

J Am Heart Assoc　10: e020760, 2021

Imai Y, Mizuno Tanaka S, Satoh M, Hirata T, Murakami Y, Miura K, Waki T, Hirata A, Sairenchi T, Irie F, Sata M, Ninomiya T, Ohkubo T, Ishikawa S, Miyamoto Y, Ohnishi H, Saitoh S, Tamakoshi A, Yamada M, Kiyama M, Iso H, Sakata K, Nakagawa H, Okayama A, Ueshima H, Okamura T; Evidence for Cardiovascular Prevention From Observational Cohorts in Japan (EPOCH‐Japan) Research Group

Prediction of lifetime risk of cardiovascular disease deaths stratified by sex in the Japanese population.

J Am Heart Assoc　10: e021753, 2021

Sasaki T, Nakagawa K, Hata J, Hirakawa Y, Shibata M, Nakano T, Tsuboi N, Oda Y, Kitazono T, Yokoo T, Ninomiya T

Pathologic diabetic nephropathy in autopsied diabetic cases with normoalbuminuria from a Japanese community-based study.

Kidney Int Rep　6: 3035-3044, 2021

Tateishi Y, Yamada Y, Katsuki M, Nagata T, Yamamoto H, Kohashi K, Koga Y, Hashisako M, Kiyozawa D, Mori T, Kuboyama Y, Kakinokizono A, Miyazaki Y, Yamaguchi A, Tsutsui H, Ninomiya T, Naiki H, Oda Y

Pathological review of cardiac amyloidosis using autopsy cases in a single Japanese institution.

Pathol Res Pract　227: 153635, 2021

Shibata M, Ohara T, Hosoi M, Hata J, Yoshida D, Hirabayashi N, Morisaki Y, Nakazawa T, Mihara A, Nagata T, Oishi E, Anno K, Sudo N, Ninomiya T

Emotional loneliness is associated with a risk of dementia in a general Japanese older population: the Hisayama Study.

J Gerontol B Psychol Sci Soc Sci　76: 1756-1766, 2021

Urushihara M, Sato H, Shimizu A, Sugiyama H, Yokoyama H, Hataya H, Matsuoka K, Okamoto T, Ogino D, Miura K, Hamada R, Hibino S, Shima Y, Yamamura T, Kitamoto K, Ishihara M, Konomoto T, Hattori M; the Committee for Renal Biopsy and Disease Registry of the Japanese Society of Nephrology( Kiyohara Y, Ninomiya T, Nagata M)

Clinical and histological features in pediatric and adolescent/young adult patients with renal disease: a cross-sectional analysis of the Japan Renal Biopsy Registry (J-RBR).

Clin Exp Nephrol　25: 1018-1026, 2021

Oshima M, Toyama T, Hara A, Shimizu M, Kitajima S, Iwata Y, Sakai N, Furuichi K, Haneda M, Babazono T, Yokoyama H, Iseki K, Araki SI, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Makino H, Wada T

Combined changes in albuminuria and kidney function and subsequent risk for kidney failure in type 2 diabetes.

BMJ Open Diabetes Res Care　9: e002311, 2021

Nakamura K, Yoshida D, Honda T, Hata J, Shibata M, Hirakawa Y, Furuta Y, Kishimoto H, Ohara T, Chen S, Kitazono T, Nakashima Y, Ninomiya T

Midlife and late-life diabetes and sarcopenia in a general older Japanese population: the Hisayama Study.

J Diabetes Investig　12: 1899-1907, 2021

NCD Risk Factor Collaboration (NCD-RisC)( Ninomiya T, Hata J)

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants.

Lancet　398: 957-980, 2021

Sasaki T, Izumaru K, Hata J, Sakata S, Oishi E, Nagata T, Tsuboi N, Oda Y, Kitazono T, Yokoo T, Ninomiya T

Serum NT-proBNP levels and histopathological myocardial fibrosis in autopsied cases from a Japanese community: the Hisayama Study.

J Cardiol　78: 237-243, 2021

Oishi E, Hata J, Honda T, Sakata S, Chen S, Hirakawa Y, Yoshida D, Shibata M, Ohara T, Furuta Y, Kitazono T, Ninomiya T

Development of a risk prediction model for incident hypertension in Japanese individuals: the Hisayama Study.

Hypertens Res　44: 1221-1229, 2021

Furuta M, Takeuchi K, Takeshita T, Shibata Y, Suma S, Kageyama S, Asakawa M, Hata J, Yoshida D, Shimazaki Y, Ninomiya T, Yamashita Y

10-year trend of tooth loss and associated factors in a Japanese population-based longitudinal study.

BMJ Open　11: e048114, 2021

Honda T, Ohara T, Yoshida D, Shibata M, Ishida Y, Furuta Y, Oishi E, Hirakawa Y, Sakata S, Hata J, Nakao T, Ninomiya T

Development of a dementia prediction model for primary care: the Hisayama Study.

Alzheimers Dement (Amst) 　13: e12221, 2021

Hata J, Nagata T, Sakata S, Oishi E, Furuta Y, Hirakawa Y, Honda T, Yoshida D, Kitazono T, Ninomiya T

Risk prediction model for incident atrial fibrillation in a general Japanese population - the Hisayama Study.

Circ J 　85: 1373-1382, 2021

Yoshikawa T, Hata J, Sakata S, Nagata T, Hirakawa Y, Hirooka Y, Tsutsui H, Kitazono T, Ninomiya T

Serum high-sensitivity C-reactive protein Levels and the development of atrial fibrillation in a general Japanese population - the Hisayama Study.

Circ J 　85: 1365-1372, 2021

Yoshinari M, Hirakawa Y, Hata J, Higashioka M, Honda T, Yoshida D, Mukai N, Nakamura U, Kitazono T, Ninomiya T

Comparison of the contributions of impaired beta cell function and insulin resistance to the development of type 2 diabetes in a Japanese community: the Hisayama Study.

Diabetologia　64: 1775-1784, 2021

Sasaki M, Miyake M, Fujiwara K, Nanba H, Akiyama M, Yanagi Y, Harada S, Tabara Y, Yasuda M, Yamashita H, Kayama T, Tsubota K, Matsuda F, Hashimoto S, Ueda E, Ninomiya T, Takebayashi T, Tsujikawa A, Sonoda KH, Kawasaki R

Cohort Profile: The Ganka-Ekigaku Network (GEN), a network of Japanese ophthalmological epidemiology studies.

Ophthalmic Epidemiol　28: 237-243, 2021

Sasaki T, Oishi E, Nagata T, Sakata S, Chen S, Furuta Y, Honda T, Yoshida D, Hata J, Tsuboi N, Kitazono T, Yokoo T, Ninomiya T

N-ｔerminal pro-B-type natriuretic peptide and incident CKD.

Kidney Int Rep　6: 976-985, 2021

Ohara T, Yoshida D, Hata J, Shibata M, Honda T, Furuta Y, Hirabayashi N, Kitazono T, Nakao T, Ninomiya T

Current status of the certification of long-term care insurance among individuals with dementia in a Japanese community: the Hisayama Study.

Psychiatry Clin Neurosci　75: 182-184, 2021

Takeshita T, Matsumoto K, Furuta M, Fukuyama S, Takeuchi K, Ogata H, Asakawa M, Kageyama S, Hata J, Ninomiya T, Inoue H, Yamashita Y

Airflow limitation and tongue microbiota in community-dwelling elderly individuals.

ERJ Open Res　7: 00616-2020, 2021

Qian F, Ardisson Korat AV, Imamura F, Marklund M, Tintle N, Virtanen JK, Zhou X, Bassett JK, Lai H, Hirakawa Y, Chien KL, Wood AC, Lankinen M, Murphy RA, Samieri C, Pertiwi K, de Mello VD, Guan W, Forouhi NG, Wareham N, Hu ICFB, Riserus U, Lind L, Harris WS, Shadyab AH, Robinson JG, Steffen LM, Hodge A, Giles GG, Ninomiya T, Uusitupa M, Tuomilehto J, Lindström J, Laakso M, Siscovick DS, Helmer C, Geleijnse JM, Wu JHY, Fretts A, Lemaitre RN, Micha R, Mozaffarian D, Sun Q; Fatty Acids and Outcomes Research Consortium (FORCE)

n-3 fatty acid biomarkers and incident type 2 diabetes: an individual participant-level pooling project of 20 prospective cohort studies.

Diabetes Care　44: 1133-1142, 2021

Kimura Y, Yoshida D, Hirakawa Y, Hata J, Honda T, Shibata M, Sakata S, Uchida K, Kitazono T, Ninomiya T

Dietary fiber intake and risk of type 2 diabetes in a general Japanese population: the Hisayama Study.

J Diabetes Investig 　12: 527-536, 2021

Yamasaki K, Hata J, Ide T, Nagata T, Sakata S, Yoshida D, Honda T, Hirakawa Y, Nakano T, Kitazono T, Tsutsui H, Ninomiya T

Urinary N-terminal pro-B-type natriuretic peptide as a biomarker for cardiovascular events in a general Japanese population: the Hisayama Study.

Environ Health Prev Med　26: 47, 2021

Harris WS, Tintle NL, Imamura F, Qian F, Korat AVA, Marklund M, Djoussé L, Bassett JK, Carmichael PH, Chen YY, Hirakawa Y, Küpers LK, Laguzzi F, Lankinen M, Murphy RA, Samieri C, Senn MK, Shi P, Virtanen JK, Brouwer IA, Chien KL, Eiriksdottir G, Forouhi NG, Geleijnse JM, Giles GG, Gudnason V, Helmer C, Hodge A, Jackson R, Khaw KT, Laakso M, Lai H, Laurin D, Leander K, Lindsay J, Micha R, Mursu J, Ninomiya T, Post W, Psaty BM, Risérus U, Robinson JG, Shadyab AH, Snetselaar L, Sala-Vila A, Sun Y, Steffen LM, Tsai MY, Wareham NJ, Wood AC, Wu JHY, Hu F, Sun Q, Siscovick DS, Lemaitre RN, Mozaffarian D; Fatty Acids and Outcomes Research Consortium (FORCE)

Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies.

Nat Commun　12: 2329, 2021

Chen S, Honda T, Hata J, Sakata S, Furuta Y, Yoshida D, Shibata M, Ohara T, Hirakawa Y, Oishi E, Kitazono T, Ninomiya T

High serum folate concentrations are associated with decreased risk of mortality among Japanese adults.

J Nutr　151: 657-665, 2021

Igarashi Y, Nochioka K, Sakata Y, Tamai T, Ohkouchi S, Irokawa T, Ogawa H, Hayashi H, Fujihashi T, Yamanaka S, Shiroto T, Miyata S, Hata J, Yamada S, Ninomiya T, Yasuda S, Kurosawa H, Shimokawa H

Risk prediction for new-onset atrial fibrillation using the Minnesota code electrocardiography classification system.

Int J Cardiol Heart Vasc　34: 100762, 2021

NCD Risk Factor Collaboration (NCD-RisC)(Ninomiya T, Hata J)

Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight.

Elife　10: e60060, 2021

Yoshimura M, Honda H, Sasagasako N, Mori S, Hamasaki H, Suzuki SO, Ishii T, Ninomiya T, Kira JI, Iwaki T

PCBP2 is downregulated in degenerating neurons and rarely observed in TDP-43-Positive inclusions in sporadic amyotrophic lateral sclerosis.

J Neuropathol Exp Neurol　80: 220-228, 2021

Gharahkhani P, Jorgenson E, Hysi P, Khawaja AP, Pendergrass S, Han X, Ong JS, Hewitt AW, Segrè AV, Rouhana JM, Hamel AR, Igo RP Jr, Choquet H, Qassim A, Josyula NS, Cooke Bailey JN, Bonnemaijer PWM, Iglesias A, Siggs OM, Young TL, Vitart V, Thiadens AAHJ, Karjalainen J, Uebe S, Melles RB, Nair KS, Luben R, Simcoe M, Amersinghe N, Cree AJ, Hohn R, Poplawski A, Chen LJ, Rong SS, Aung T, Vithana EN; NEIGHBORHOOD consortium; ANZRAG consortium; Biobank Japan project(Kiyohara Y, Ninomiya T); FinnGen study; UK Biobank Eye and Vision Consortium; GIGA study group; 23 and Me Research Team, Tamiya G, Shiga Y, Yamamoto M, Nakazawa T, Currant H, Birney E, Wang X, Auton A, Lupton MK, Martin NG, Ashaye A, Olawoye O, Williams SE, Akafo S, Ramsay M, Hashimoto K, Kamatani Y, Akiyama M, Momozawa Y, Foster PJ, Khaw PT, Morgan JE, Strouthidis NG, Kraft P, Kang JH, Pang CP, Pasutto F, Mitchell P, Lotery AJ, Palotie A, van Duijn C, Haines JL, Hammond C, Pasquale LR, Klaver CCW, Hauser M, Khor CC, Mackey DA, Kubo M, Cheng CY, Craig JE, MacGregor S, Wiggs JL

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries.

Nat Commun　12: 1258, 2021

Nakamura K, Yoshida D, Honda T, Hata J, Shibata M, Hirakawa Y, Furuta Y, Kishimoto H, Ohara T, Kitazono T, Nakashima Y, Ninomiya T

Prevalence and mortality of sarcopenia in a community-dwelling older Japanese population: the Hisayama Study.

J Epidemiol　31: 320-327, 2021

Shikata K, Haneda M, Ninomiya T, Koya D, Suzuki Y, Suzuki D, Ishida H, Akai H, Tomino Y, Uzu T, Nishimura M, Maeda S, Ogawa D, Miyamoto S, Makino H; Diabetic Nephropathy Remission and Regression Team Trial in Japan (DNETT-Japan) collaborative group

Randomized trial of an intensified, multifactorial intervention in patients with advanced-stage diabetic kidney disease: Diabetic Nephropathy Remission and Regression Team Trial in Japan (DNETT-Japan).

J Diabetes Investig　12: 207-216, 2021

Higashioka M, Sakata S, Honda T, Hata J, Shibata M, Yoshida D, Goto K, Kitazono T, Osawa H, Ninomiya T

The association of small dense low-density lipoprotein cholesterol and coronary heart disease in subjects at high cardiovascular risk.

J Atheroscler Thromb　28: 79-89, 2021