Results
Tajimi T, Furuta Y, Hirabayashi N, Honda T, Hata J, Ohara T, Shibata M, Nakao T, Kitazono T, Nakashima Y, Ninomiya T
Association of gait speed with regional brain volumes and risk of dementia in older Japanese: the Hisayama Study.
Arch Gerontol Geriatr 106: 104883, 2023pubmed
Noguchi-Shinohara M, Hamaguchi T, Sakai K, Komatsu J, Iwasa K, Horimoto M, Nakamura H, Yamada M, Ono K
Effects of Melissa Officinalis Extract containing Rosmarinic Acid on cognition in older adults without dementia: a Randomized Controlled Trial.
J Alzheimers Dis 91: 805-814, 2023pubmed
Ueda E, Hirabayashi N, Ohara T, Hata J, Honda T, Fujiwara K, Furuta Y, Shibata M, Hashimoto S, Nakamura S, Nakazawa T, Nakao T, Kitazono T, Ninomiya T, Sonoda KH
Association of inner retinal thickness with prevalent dementia and brain atrophy in a general older population: the Hisayama Study.
Ophthalmol Sci 2: 100157, 2022pubmed
Mihara A, Ohara T, Hata J, Chen S, Honda T, Tamrakar S, Isa A, Wang D, Shimizu K, Katakura Y, Yonemoto K, Nakao T, Kitazono T, Ninomiya T
Association of serum s-adenosylmethionine, s-adenosylhomocysteine, and their ratio with the risk of dementia and death in a community.
Sci Rep 12: 12427, 2022pubmed
Ohara T, Hata J, Tanaka M, Honda T, Yamakage H, Inoue T, Hirakawa Y, Kusakabe T, Shibata M, Kitazono T, Nakao T, Satoh-Asahara N, Ninomiya T
Association of daily sleep duration with the incident dementia by serum soluble TREM2 in a community.
J Am Geriatr Soc 70: 1147-1156, 2022pubmed
Hirabayashi N, Hata J, Furuta Y, Ohara T, Shibata M, Hirakawa Y, Yamashita F, Yoshihara K, Kitazono T, Sudo N, Ninomiya T
Association between diabetes and gray matter atrophy patterns in a general older Japanese population: the Hisayama Study.
Diabetes Care 45: 1364-1371, 2022pubmed
Kimura Y, Yoshida D, Ohara T, Hata J, Honda T, Hirakawa Y, Shibata M, Oishi E, Sakata S, Furuta Y, Chen S, Uchida K, Nakao T, Kitazono T, Ninomiya T
Long-term association of vegetable and fruit intake with risk of dementia in Japanese older adults: the Hisayama Study.
BMC Geriatr 22: 257, 2022pubmed
Hidaka Y, Hashimoto M, Suehiro T, Fukuhara R, Ishikawa T, Tsunoda N, Koyama A, Honda K, Miyagawa Y, Yoshiura K, Boku S, Ishii K, Ikeda M, Takebayashi M
Impact of age on the cerebrospinal fluid spaces: high-convexity and medial subarachnoid spaces decrease with age.
Fluids Barriers CNS 19: 82, 2022pubmed
Yoshiura K, Fukuhara R, Ishikawa T, Tsunoda N, Koyama A, Miyagawa Y, Hidaka Y, Hashimoto M, Ikeda M, Takebayashi M, Shimodozono M
Brain structural alterations and clinical features of cognitive frailty in Japanese community-dwelling older adults: the Arao study (JPSC-AD).
Sci Rep 12: 8202, 2022pubmed
Kawakami I, Iga JI, Takahashi S, Lin YT, Fujishiro H
Towards an understanding of the pathological basis of senile depression and incident dementia: Implications for treatment.
Psychiatry Clin Neurosci 76: 620-632, 2022pubmed
Mori H, Yoshino Y, Ueno M, Funahashi Y, Kumon H, Ozaki Y, Yamazaki K, Ochi S, Iga JI, Ueno SI
Blood MAPT expression and methylation status in Alzheimer's disease.
Psychiatry and Clinical Neurosciences Reports e65, 2022
Ozaki T, Yoshino Y, Tachibana A, Shimizu H, Mori T, Nakayama T, Mawatari K, Numata S, Iga JI, Takahashi A, Ohmori T, Ueno SI
Metabolomic alterations in the blood plasma of older adults with mild cognitive impairment and Alzheimer's disease (from the Nakayama Study).
Sci Rep 12: 15205, 2022pubmed
Shimizu H, Mori T, Yoshida T, Tachibana A, Ozaki T, Yoshino Y, Ochi S, Sonobe N, Matsumoto T, Komori K, Iga JI, Ninomiya T, Ueno SI, Ikeda M
Secular trends in the prevalence of dementia based on a community-based complete enumeration in Japan: the Nakayama Study.
Psychogeriatrics 22: 631-641, 2022pubmed
Ueno M, Yoshino Y, Mori H, Funahashi Y, Kumon H, Ochi S, Ozaki T, Tachibana A, Yoshida T, Shimizu H, Mori T, Iga JI, Ueno SI
Association Study and Meta-Analysis of Polymorphisms and Blood mRNA Expression of the ALDH2 Gene in Patients with Alzheimer's Disease.
J Alzheimers Dis 87: 863-871, 2022 pubmed
Nonaka M, Komori Y, Isozaki H, Ueno K, Kamei T, Takeda J, Nonaka Y, Yabe I, Zaitsu M, Nakashima K, Asai A
Current status and challenges of neurosurgical procedures for patients with myelomeningocele in real-world Japan.
Childs Nerv Syst Epub ahead of print, 2022pubmed
Nonaka M, Isozaki H, Komori Y, Kamei T, Takeda J, Nonaka Y, Yabe I, Zaitsu M, Nakashima K, Asai A
Number of surgeries performed during the lifetime of patients with myelomeningocele.
J Neurosurg Pediatr 18: 1-9, 2022pubmed
Ito M, Yamauchi A, Urano M, Kato T, Matsuo M, Nakashima K, Saito K
Epidemiological investigation of spinal muscular atrophy in Japan.
Brain Dev 44: 2-16, 2022pubmed
Noguchi-Shinohara M, Ono K, Yuki-Nozaki S, Iwasa K, Yokogawa M, Komai K, Thyreau B, Tatewaki Y, Taki Y, Shibata M, Ohara T, Hata J, Ninomiya T, Yamada M
Association of the prefrailty with global brain atrophy and white matter lesions among cognitively unimpaired older adults: the Nakajima study.
Sci Rep 12: 12129, 2022pubmed
Taguchi K, Iwaoka K, Yamaguchi T, Nozaki R, Sato Y, Terauchi T, Suzuki Y, Takahashi K, Takahashi K, Akasaka H, Ishizuka N, Maeda T
A cross-sectional study of Parkinson's disease and the prodromal phase in community-dwelling older adults in eastern Japan.
Clin Park Relat Disord 7: 100147, 2022pubmed
Nakazawa T, Ohara T, Hirabayashi N, Furuta Y, Hata J, Shibata M, Honda T, Kitazono T, Nakao T, Ninomiya T
Multiple-region grey matter atrophy as a predictor for the development of dementia in a community: the Hisayama Study.
J Neurol Neurosurg Psychiatry 93: 263-271, 2022pubmed
Sone D, Beheshiti I, Shinagawa S, Niimura H, Kobayashi N, Kida H, Shikimoto R, Noda Y, Nakajima S, Bun S, Mimura M, Shigeta M
Neuroimaging-derived brain age is associated with life satisfaction in cognitively unimpaired elderly: A community-based study.
Transl Psychiatry 12: 25, 2022pubmed
Mai Y, Izumi K, Sawada K, Akasaka E, Mai S, Sawamura D, Ihara K, Nakaji S, Nishie W.
A 1,035-Subject Study Suggesting a History of Bone Fracture as a Possible Factor Associated with the Development of Anti-BP180 Autoantibodies.
J Invest Dermatol 142: 984-987, 2022pubmed
Kaneda M, Wai KM, Kanda A, Ando M, Murashita K, Nakaji S, Ihara K.
Low Level of Serum Cadmium in Relation to Blood Pressures Among Japanese General Population.
Biol Trace Elem Res 200: 67-75, 2022pubmed
Shibata M, Ohara T, Hosoi M, Hata J, Yoshida D, Hirabayashi N, Morisaki Y, Nakazawa T, Mihara A, Nagata T, Oishi E, Anno K, Sudo N, Ninomiya T
Emotional loneliness is associated with a risk of dementia in a general Japanese older population: the Hisayama Study.
J Gerontol B Psychol Sci Soc Sci 76: 1756-1766, 2021pubmed
Nakamura K, Yoshida D, Honda T, Hata J, Shibata M, Hirakawa Y, Furuta Y, Kishimoto H, Ohara T, Chen S, Kitazono T, Nakashima Y, Ninomiya T
Midlife and late-life diabetes and sarcopenia in a general older Japanese population: the Hisayama Study.
J Diabetes Investig 12: 1899-1907, 2021pubmed
Honda T, Ohara T, Yoshida D, Shibata M, Ishida Y, Furuta Y, Oishi E, Hirakawa Y, Sakata S, Hata J, Nakao T, Ninomiya T
Development of a dementia prediction model for primary care: the Hisayama Study.
Alzheimers Dement (Amst) 13: e12221, 2021pubmed
Ohara T, Yoshida D, Hata J, Shibata M, Honda T, Furuta Y, Hirabayashi N, Kitazono T, Nakao T, Ninomiya T
Current status of the certification of long-term care insurance among individuals with dementia in a Japanese community: the Hisayama Study.
Psychiatry Clin Neurosci 75: 182-184, 2021pubmed
Yamasaki K, Hata J, Ide T, Nagata T, Sakata S, Yoshida D, Honda T, Hirakawa Y, Nakano T, Kitazono T, Tsutsui H, Ninomiya T
Urinary N-terminal pro-B-type natriuretic peptide as a biomarker for cardiovascular events in a general Japanese population: the Hisayama Study.
Environ Health Prev Med 26: 47, 2021pubmed
Chen S, Honda T, Hata J, Sakata S, Furuta Y, Yoshida D, Shibata M, Ohara T, Hirakawa Y, Oishi E, Kitazono T, Ninomiya T
High serum folate concentrations are associated with decreased risk of mortality among Japanese adults.
J Nutr 151: 657-665, 2021pubmed
Nakamura K, Yoshida D, Honda T, Hata J, Shibata M, Hirakawa Y, Furuta Y, Kishimoto H, Ohara T, Kitazono T, Nakashima Y, Ninomiya T
Prevalence and mortality of sarcopenia in a community-dwelling older Japanese population: the Hisayama Study.
J Epidemiol 31: 320-327, 2021pubmed
Kumon H, Yoshino Y, Funahashi Y, Mori H, Ueno M, Ozaki Y, Yamazaki K, Ochi S, Mori T, Iga JI, Nagai M, Nomoto M, Ueno SI
PICALM mRNA Expression in the Blood of Patients with Neurodegenerative Diseases and Geriatric Depression.
J Alzheimers Dis 79: 1055-1062, 2021pubmed
Mori H, Funahashi Y, Yoshino Y, Kumon H, Ozaki Y, Yamazaki K, Ochi S, Tachibana A, Yoshida T, Shimizu H, Mori T, Iga JI, Ueno SI
Blood CDKN2A Gene Expression in Aging and Neurodegenerative Diseases.
J Alzheimers Dis 82: 1737-1744, 2021pubmed
Yoshino Y, Kumon H, Mori T, Yoshida T, Tachibana A, Shimizu H, Iga JI, Ueno SI
Effects of AGXT2 variants on blood pressure and blood sugar among 750 older Japanese subjects recruited by the complete enumeration survey method.
BMC Genomics 22: 287, 2021pubmed
Shikimoto R, Noda Y, Kida H, Nakajima S, Tsugawa S, Mimura Y, Ochi R, Takayama M, Niimura H, Mimura M
Association between resilience and cortical thickness in the posterior cingulate cortex and the temporal pole in Japanese older people: A population-based cross-sectional study.
J Psychiatr Res 142: 89-100, 2021pubmed
Ichinohe M, Wada K, Kumagai G, Tanaka S, Asari T, Takeda O, Ota S, Koyama K, Ihara K, Nakaji S, Ishibashi Y
Prevalence and associated factors of radiographic vertebral fractures in men: Rural population cross-sectional observation study in Japan.
J Orthop Sci 26: 572-576, 2021pubmed
Wai KM,Sawada K, Itoh K, Okuyama S, Uchikawa Y, Hayashi S, Shiraki A, Murashita K, Nakaji S, Ihara K.
Telomere Length and Arterial Stiffness Reflected by Brachial-Ankle Pulse Wave Velocity: A Population-Based Cross-Sectional Study.
J Pers Med 11: 1278, 2021pubmed
Ozato N, Saitou S, Yamaguchi T, Katashima M, Misawa M, Jung S, Mori K, Kawada H, Katsuragi Y, Mikami T, Nakaji S.
Association between Visceral Fat and Brain Structural Changes or Cognitive Function.
Brain Sci 11: 1036, 2021pubmed
Ikegame T, Hidaka Y, Nakachi Y, Murata Y, Watanabe R, Sugawara H, Asai T, Kiyota E, Saito T, Ikeda M, Sasaki T, Hashimoto M, Ishikawa T,Takebayashi M,Iwata N, Kakiuchi C, Kato T, Kasai K, Bundo M, Iwamoto K
Identification and functional characterization of the extremely long allele of the serotonin transporter-linked polymorphic region.
Translational Psychiatry 11: 119, 2021pubmed
Watanabe Y, Ogino M, Ichikawa H, Hanajima R, Nakashima K
The Edinburgh Cognitive and Behavioural ALS Screen (ECAS) for Japanese ALS and FTD patients.
Amyotroph Lateral Scler Frontotemporal Degener 22: 66-72, 2021pubmed
Akiyama M
Multi-omics study for interpretation of genome-wide association study.
J Hum Genet 66: 3–10, 2021pubmed
Ikezaki H, Hashimoto M, Ishikawa T, Fukuhara R, Tanaka H, Yuki S, Kuribayashi K, Hotta M, Koyama A, Ikeda M, Takebayashi M
Relationship between executive dysfunction and neuropsychiatric symptoms and impaired instrumental activities of daily living among patients with very mild Alzheimer's disease.
Int J Geriatr Psychiatry 35: 877-887, 2020pubmed
Han G, Maruta M, Ikeda Y, Ishikawa T, Tanaka H, Koyama A, Fukuhara R, Boku S, Takebayashi M, Tabira T
Relationship between performance on the Mini-Mental StateExamination sub-items and activities of daily living in patients with Alzheimer's Disease.
J Clin Med 9: 1537, 2020pubmed
Okada-Tsuchioka M, Omori W, Kajitani N, Shibasaki C, Itagaki K,Takebayashi M
Decreased serum levels of thrombospondin-1 in female depressed patients.
Neuropsychopharmacol Rep 40: 39-45, 2020pubmed
小森 憲治郎, 武田 直也, 森 崇明, 吉田 卓, 豊田 泰孝, 谷向 知
語義失語再考
高次脳機能研究 40: 272-279, 2020
Kishi M,Wada-Isoe K, Hanajima R, Nakashima K
Predictors for Incident Mild Parkinsonian Signs in Older Japanese.
Yonago Acta Medica 63: 1–7, 2020pubmed
Sawada M, Wada-Isoe K, Nakashita S, Maeda T, Hanajima R, Nakashima K
Personality traits associated with freezing of gait in Parkinson's disease patients.
Parkinsonism Relat Disord 81: 67-68, 2020pubmed
Niimura H, Eguchi Y, Kida H, Suzuki K, Takayama M, Mimura M
Sociopsychological characteristics of late nonagenarians in Japan: The protocol of the Arakawa 95+ cohort study.
Psychogeriatrics 20: 50-58, 2020pubmed
Suzuki K, Niimura H, Kida H, Eguchi Y, Kitashima C, Takayama M,Mimura M
Increasing light physical activity helps to maintain cognitive function among the community-dwelling oldest old population: A cross-sectional study using actigraph from the Arakawa 85+ study.
Geriatr Gerontol Int 20: 773-778, 2020pubmed
Kobayashi N, Shinagawa S, Niimura H, Kida H, Nagata T, Tagai K, Shimada K, Oka N, Ryo Shikimoto, Noda Y, Nakajima S, Saito T, Saido TC,Mimur M, Shigeta M, Kondo K
Increased blood COASY DNA methylation levels a potential biomarker for early pathology of Alzheimer’s disease.
Sci Rep 10: 12217, 2020pubmed
Noguchi-Shinohara M, Domoto C, Yoshida T, Niwa K, Yuki-Nozaki S, Samuraki-Yokohama M, Sakai K, Hamaguchi T, Ono K, Iwasa K, Matsunari I, Komai K, Nakamura H, Yamada M
A new computerized assessment battery for cognition (C-ABC) to detect mild cognitive impairment and dementia around 5 min.
PLoS ONE 15: e0243469, 2020pubmed
Ikeda Y, Kikuchi M, Noguchi-Shinohara M, Iwasa K, Kameya M, Hirosawa T, Yoshita M, Ono K, Samuraki-Yokohama M, Yamada M
Spontaneous MEG activity of the cerebral cortex during eyes closed and open discriminates Alzheimer’s disease from cognitively normal older adults.
Sci Rep 10: 9132, 2020pubmed
Noguchi‑Shinohara M, Ono K, Hamaguchi T, Nagai T, Kobayashi S, Komatsu J, Samuraki‑Yokohama M, Iwasa K, Yokoyama K, Nakamura H, Yamada M
Safety and efficacy of Melissa officinalis extract containing rosmarinic acid in the prevention of Alzheimer’s disease progression.
Sci Rep 10: 18627, 2020pubmed
赤坂博、米澤久司、高橋純子、小原智子、柴田俊秀、鈴木真紗子、石塚直樹、佐藤光信、工藤雅子、寺山靖夫、前田哲也
MCI・早期アルツハイマー病の短時間スクリーニング法の検討―老研式活動能力指標の自己評価と家族評価を用いて―
日老医誌 57: 182-194, 2020pubmed
Sakata S, Hata J, Honda T, Hirakawa Y, Oishi E, Shibata M, Yoshida D, Goto K, Kitazono T, Ninomiya T
Serum uric acid levels and cardiovascular mortality in a general Japanese population: the Hisayama Study.
Hypertens Res 43: 560-568, 2020pubmed
Nagata T, Hata J, Sakata S, Oishi E, Honda T, Furuta Y, Ohara T, Yoshida D, Hirakawa Y, Shibata M, Ide T, Kitazono T, Tsutsui H, Ninomiya T
Serum N-terminal pro-B-type natriuretic peptide as a predictor for future development of atrial fibrillation in a general population: the Hisayama Study.
Int J Cardiol 320: 90-96, 2020pubmed
Ishida Y, Yoshida D, Honda T, Hirakawa Y, Shibata M, Sakata S, Furuta Y, Oishi E, Hata J, Kitazono T, Ninomiya T
Influence of the accumulation of unhealthy eating habits on obesity in a general Japanese population: the Hisayama Study.
Nutrients 12: 3160, 2020pubmed
二宮利治
【認知症施策-最近の動向-】進行を少しでも遅らせ、穏やかに生きる手助けをする(予防) 健康長寿社会の実現を目指した大規模認知症コホート研究.
Geriatric Medicine 58: 515-519, 2020
Yoshida D, Ohara T, Hata J, Shibata M, Hirakawa Y, Honda T, Furuta Y, Oishi E, Sakata S, Kanba S, Kitazono T, Ninomiya T
Lifetime cumulative incidence of dementia in a community-dwelling elderly population in Japan.
Neurology 95: e508-e518, 2020pubmed
Mihara A, Ohara T, Hata J, Honda T, Chen S, Sakata S, Oishi E, Hirakawa Y, Nakao T, Kitazono T, Ninomiya T
Association between serum glycated albumin and risk of cardiovascular disease in a Japanese community: the Hisayama Study.
Atherosclerosis 311: 52-59, 2020pubmed
Ohara T, Furuta Y, Hirabayashi N, Hata J, Hirakawa Y, Honda T, Yoshida D, Shibata M, Kitazono T, Ninomiya T
Elevated serum glycated albumin and glycated albumin : hemoglobin A(1c) ratio were associated with hippocampal atrophy in a general elderly population of Japanese: the Hisayama Study.
J Diabetes Investig 11: 971-979, 2020pubmed
Yamasaki K, Hata J, Furuta Y, Hirabayashi N, Ohara T, Yoshida D, Hirakawa Y, Nakano T, Kitazono T, Ninomiya T
Association of albuminuria with white matter hyperintensities volume on brain magnetic resonance imaging in elderly Japanese - the Hisayama Study.
Circ J 84: 935-942, 2020pubmed
Hachiya T, Hata J, Hirakawa Y, Yoshida D, Furuta Y, Kitazono T, Shimizu A, Ninomiya T
Genome-wide polygenic score and the risk of ischemic stroke in a prospective cohort: the Hisayama Study.
Stroke 51: 759-765, 2020pubmed
Chen S, Honda T, Ohara T, Hata J, Hirakawa Y, Yoshida D, Shibata M, Sakata S, Oishi E, Furuta Y, Kitazono T, Ninomiya T
Serum homocysteine and risk of dementia in Japan.
J Neurol Neurosurg Psychiatry 91: 540-546, 2020pubmed
Nakanishi M, Igarashi A, Ueda K, Brnabic AJM, Treuer T, Sato M, Kahle-Wrobleski K, Meguro K, Yamada M, Mimura M, Arai H
Costs and Resource Use associated with community-dwelling patients with Alzheimer’s disease in Japan: Baseline results from the prospective observational GERAS-J Study.
J Alzheimers Dis 74:127-138, 2020pubmed
Kida H, Nakajima S, Shikimoto R, Ochi R, Noda Y, Tsugawa S, Fujii S, Takayama M, Mimura M, Niimura H
Approach-oriented coping strategy level may be related to volume of the whole hippocampus in the elderly.
Psychiatry Clin Neurosci 74: 270–276, 2020pubmed
Niimura H, Eguchi Y, Kida H, Suzuki K, Takayama M, Mimura M
Sociopsychological characteristics of late nonagenarians in Japan: The protocol of the Arakawa 95+ study.
Psychogeriatrics 20: 50-58, 2020pubmed
Tajiri Y,Wada-Isoe K, Tanaka K, Adachi T,Hanajima R,Nakashima K
A Single-institution Study on Predictors of Short-term Progression from Mild Cognitive Impairment in Parkinson's Disease to Parkinson's Disease with Dementia.
Yonago Acta Med 63: 28-33, 2020pubmed
Ozaki Y, Yoshino Y, Yamazaki K, Ochi S, Iga JI, Nagai M, Nomoto M, Ueno SI
DRD2 methylation to differentiate dementia with Lewy bodies from Parkinson's disease.
Acta Neurol Scand 141: 177-182, 2020.pubmed
Hatabe Y, Shibata M, Ohara T, Oishi E, Yoshida D, Honda T, Hata J, Kanba S, Kitazono T, Ninomiya T
Decline in handgrip strength from midlife to late-life is associated with dementia in a Japanese community: the Hisayama Study.
J Epidemiol 30: 15-23, 2020.pubmed
田宮 沙紀,田辺 紗矢佳,南 花枝,井上 紗央里,藤井 彩,中島理絵,大盛 航,町野 彰彦,竹林 実
臨床心理士の精神科リエゾンにおける活動概要及び適応事例の後方視的検討.
精神科治療学 印刷中
Okada-Tsuchioka M,Omori W,Kajitani N,Shibasaki C,Itagaki K,Takebayashi M.
Decreased serum levels of thrombospondin-1 in female depressed patients.
Neuropsychopharmacol Rep 40: 39-45, 2020pubmed
清水 秀明, 小森 憲治郎, 豊田 泰孝, 吉田 卓, 越智 紳一郎, 森 崇明, 池田 学
常同行動に及ぼす意味記憶障害の影響について-意味性認知症例の行動観察より-
神経心理学 35: 225-237, 2019
Ota S, Chiba D, Sasaki E, Kumagai G, Yamamoto Y, Nakaji S, Tsuda E, Ishibashi Y
Symptomatic bone marrow lesions induced by reduced bone mineral density in middle-aged women: a cross-sectional Japanese population study.
Arthritis Res Ther 21: 113, 2019pubmed
Satake A, Kobayashi W, Tamura Y, Oyama T, Fukuta H, Inui A, Sawada K, Ihara K, Noguchi T, Murashita K, Nakaji S
Effects of oral environment on frailty: particular relevance of tongue pressure.
Clin Interv Aging 14: 1643-1468, 2019pubmed
佐藤 光信, 米澤 久司, 工藤 雅子, 柴田 俊秀, 小原 智子, 鈴木 真紗子, 石塚 直樹, 高橋 純子, 寺山 靖夫
アルツハイマー病における病期別記銘・保持能力の検討.
日本老年医学会雑誌 56: 273-282, 2019pubmed
Noguchi-Shinohara M, Hirako K, Fujiu M, Sagae M, Samuta H, Nakamura H, Yamada M
Presence of a synergistic interaction between current cigarette smoking and diabetes mellitus on development of dementia in older adults.
J Alzheimers Dis 71: 833-840, 2019pubmed
Hase T, Shishido S, Yamamoto S, Yamashita R, Nukima H, Taira S, Toyoda T, Abe K, Hamaguchi T, Ono K, Noguchi-Shinohara M, Yamada M, Kobayashi S
Rosmarinic acid suppresses Alzheimer's disease development by reducing amyloid beta aggregation by increasing monoamine secretion.
Sci Rep 9: 8711, 2019pubmed
Sawada M, Wada-Isoe K, Hanajima R, Nakashima K
Clinical features of freezing of gait in Parkinson's disease patients.
Brain Behav 9: e01244, 2019. Epub 2019 Mar 9.pubmed
Nakanishi M, Watanabe Y, Honda N, Une M, Kazuki K,Kazuki Y,Terashima T, Katagi M, Nakashima K, Hanajima R
Dynamics of host and graft after cell sheet transplantation: Basic study for the application of amyotrophic lateral sclerosis.
Brain Res 1724: 146444, 2019 Epub 2019 sep 10.pubmed
Kishi M, Wada-Isoe K,Hanajima R, Nakashima K
Predictors for incident mild parkinsonian signs in older Japanese.
Yonago Acta Med 63: 1-7, 2019pubmed
清水 秀明, 小森 憲治郎, 豊田 泰孝, 吉田 卓, 越智 紳一郎, 森 崇明, 池田 学
常同行動に及ぼす意味記憶障害の影響について 意味性認知症例の行動観察より
神経心理学 35: 225-237, 2019
Ochi S, Mori T, Iga JI, Ueno SI
Dose-Dependent Efficacy of Tandospirone for an Oldest-Old Patient With Behavioral and Psychological Symptoms of Dementia.
J Clin Psychopharmacol 39: 176-178, 2019pubmed
二宮 利治
久山町研究からみた認知症対策.
bios 24-Ⅳ: 3-6, 2019
二宮 利治
特集:糖尿病と認知症~その「危険な関係」を知る~.Ⅰ.疫学 糖尿病と認知症の疫学:久山町研究.
月刊糖尿病 116: 6-13, 2019
二宮 利治
Ⅰ.一般住民コホート研究.1.生活習慣病と認知症の関係:久山町研究.
The Lipid 30: 12-18, 2019
二宮 利治
認知症の有病率・発症率と危険因子-久山町研究より-.
精神科臨床Legato 5: 18-23, 2019
大石 絵美、二宮 利治
特集:脳血管と認知症.診断・臨床 高血圧および血圧変動と認知症.
最新医学 74: 49-57, 2019
Honda T, Ohara T, Shinohara M, Hata J, Toh R, Yoshida D, Shibata M, Ishida T, Hirakawa Y, Irino Y, Sakata S, Uchida K, Kitazono T, Kanba S, Hirata KI, Ninomiya T
Serum elaidic acid concentration and risk of dementia: the Hisayama Study.
Neurology 93: e2053-e2064, 2019. Epub 2019 Oct 23. pubmed
Nagata T, Ohara T, Hata J, Sakata S, Furuta Y, Yoshida D, Honda T, Hirakawa Y, Ide T, Kanba S, Kitazono T, Tsutsui H, Ninomiya T
NT-proBNP and risk of dementia in a general Japanese elderly population: the Hisayama Study.
J Am Heart Assoc 8: e011652, 2019. Epub 2019 Aug 24.pubmed
Yoshida D, Ohara T, Hata J, Shibata M, Hirakawa Y, Honda T, Uchida K, Takasugi S, Kitazono T, Kiyohara Y, Ninomiya T
Dairy consumption and risk of functional disability in an elderly Japanese population: the Hisayama Study.
Am J Clin Nutr 109: 1664-1671, 2019pubmed
Ohara T, Hata J, Tanaka M, Honda T, Yamakage H, Yoshida D, Inoue T, Hirakawa Y, Kusakabe T, Shibata M, Teraoka T, Kitazono T, Kanba S, Satoh-Asahara N, Ninomiya T
Serum soluble triggering receptor expressed on myeloid cells 2 as a biomarker for incident dementia: the Hisayama Study.
Ann Neurol 85: 47-58, 2019pubmed
丸田 道雄,田平 隆行,宮田 浩紀,堀田 牧,吉満 考二,韓 侊熙,髙橋 弘樹,川越 雅弘
BPSD関連項目に該当する要支援高齢者の介護度悪化に関わる要因の検討
機関誌『保健医療学雑誌』 19: 19-26, 2019
重松 潤,松本 美涼,田辺 紗矢佳,南 花枝,竹林 実,尾形 明子
看護学生における反すう・自動思考がバーンアウトに及ぼす影響.
ストレス科学研究 34: 38-44, 2019
南 花枝,田辺 紗矢佳,田宮 沙紀,町野 彰彦,竹林 実
呉医療センターにおける発達的問題を抱えた小児の支援に臨床心理士が果たす役割について.
広島医学 72: 295-300, 2019
神垣 伸,大盛 航,板垣 圭,竹林 実
クロザピンによる治療中にけいれん発作が出現した統合失調症の一例.
精神医学 61: 103-107, 2019
Hatada Y,Hashimoto M,Shiraishi S,Ishikawa T,Fukuhara R,Yuki S,Tanaka H,Miyagawa Y,Kitajima M,Uetani H,Tsunoda N,Koyama A,Ikeda M
Cerebral Microbleeds Are Associated with Cerebral Hypoperfusion in Patients with Alzheimer's Disease.
J Alzheimers Dis 71: 273-280, 2019pubmed
Omori W,Itagaki K,Kajitani N,Abe H,Okada-Tsuchioka M,Okamoto Y,Takebayashi M
Shared preventive factors associated with relapse after a response to electroconvulsive therapy in four major psychiatric disorders.
Psychiatry Clin Neurosci 73 : 494-500, 2019pubmed
Itagaki K,Takebayashi M,Abe H,Shibasaki C,Kajitani N,Okada-Tsuchioka M,Hattori K,Yoshida S,Kunugi H,Yamawaki S
Reduced serum and cerebrospinal fluid levels of autotaxin in major depressive disorder.
Int J Neuropsychopharmacol 22: 261-269, 2019pubmed
Tateishi M, Kitajima M, Hirai T, Yoneda T, Hashimoto M, Kurehana N, Uetani H, Fukuhara R, Azuma M, Yamashita Y
Differentiating between Alzheimer Disease Patients and Controls with Phase-difference-enhanced Imaging at 3T: A Feasibility Study.
Magn Reson Med Sci 17: 283-292, 2018 pubmed
Tsunoda N,Hashimoto M,Ishikawa T,Fukuhara R,Yuki S,Tanaka T,Hatada Y,Miyagawa Y,Ikeda M
Clinical Features of Auditory Hallucinations in Patients With Dementia With Lewy Bodies: A Soundtrack of Visual Hallucinations.
J Clin Psychiatry 79: 17m11623, 2018pubmed
Matsushita M,Yatabe Y,Koyama A,Katsuya A,Ijichi D,Miyagawa Y,Ikezaki H,Furukawa N,Ikeda M,Hashimoto M
Are saving appearance responses typical communication patterns in Alzheimer's disease?
PLoS One 13: e0197468, 2018pubmed
Fukuda K,Terada S,Hashimoto M,Ukai K,Kumagai R,Suzuki M,Nagaya M,Yoshida M,Hattori H,Murotani K,Toba K
Effectiveness of educational program using printed educational material on care burden distress among staff of residential aged care facilities without medical specialists and/or registered nurses: Cluster quasi-randomization study.
Geriatr Gerontol Int 18: 487-494, 2018 pubmed
Koyama A, Hashimoto M, Fukuhara R, Ichimi N, Takasaki A, Matsushita M, Ishikawa T, Tanaka H, Miyagawa Y, Ikeda M
Caregiver Burden in Semantic Dementia with Right- and Left-Sided Predominant Cerebral Atrophy and in Behavioral-Variant Frontotemporal Dementia.
Dement Geriatr Cogn Disord Extra 8: 128-137, 2018pubmed
佐々木 博之,松本 武士,城野 匡,弟子丸 元紀
児童・思春期の大うつ病性障害の症状軽減時期把握のための研究.
精神科治療学 33: 761-767, 2018
橋本 衛
軽度認知障害と森田療法.
日本森田療法学会雑誌 29: 35-41, 2018
Ninomiya T
Chapter6. Epidemiology of dementia in a community: the Hisayama Study.
Health Issues and Care System for the Elderly, Washio M, Kiyohara C (editors), Springer pp83-95, 2018
Ohara T, Honda T, Hata J, Yoshida D, Mukai N, Hirakawa Y, Shibata M, Kishimoto H, Kitazono T, Kanba S, Ninomiya T
Association between daily sleep duration and risk of dementia and mortality in a Japanese community.
J Am Geriatr Soc 66: 1911-1918, 2018pubmed
Shibata M, Ohara T, Yoshida D, Hata J, Mukai N, Kawano H, Kanba S, Kitazono T, Ninomiya T
Association between the ratio of serum arachidonic acid to eicosapentaenoic acid and the presence of depressive symptoms in a general Japanese population: the Hisayama Study.
J Affect Disord 237: 73-79, 2018pubmed
小原 知之、二宮 利治
Ⅳ.認知症予防. 久山町研究から考える認知症予防.
日本臨牀 76: 182-187, 2018
Takae K, Hata J, Ohara T, Yoshida D, Shibata M, Mukai N, Hirakawa Y, Kishimoto H, Tsuruya K, Kitazono T, Kiyohara Y, Ninomiya T
Albuminuria increases the risks for both alzheimer disease and vascular dementia in community-dwelling Japanese elderly: the Hisayama Study.
J Am Heart Assoc 7: e006693, 2018pubmed
Sao T, Yoshino Y, Yamazaki K, Ozaki Y, Mori Y, Ochi S, Yoshida T, Mori T, Iga JI, Ueno SI
MEF2C mRNA expression and cognitive function in Japanese patients with Alzheimer's disease.
Psychiatry Clin Neurosci 72: 160-167, 2018pubmed
Sao T, Yoshino Y, Yamazaki K, Ozaki Y, Mori Y, Ochi S, Yoshida T, Mori T, Iga JI, Ueno SI
TREM1 mRNA Expression in Leukocytes and Cognitive Function in Japanese Patients with Alzheimer's Disease.
J Alzheimers Dis 64: 1275-1284, 2018pubmed
Yoshino Y, Funahashi Y, Nakata S, Ozaki Y, Yamazaki K, Yoshida T, Mori T, Mori Y, Ochi S, Iga JI, Ueno SI
Ghrelin cascade changes in the peripheral blood of Japanese patients with Alzheimer's disease.
J Psychiatr Res 107: 79-85, 2018pubmed
Ando R, Iwaki H, Tsujii T, Nagai M, Nishikawa N, Yabe H, Aiba I, Hasegawa K, Tsuboi Y, Aoki M, Nakashima K, Nomoto M, Parkinson's Disease Safe Driving Study Group of Japan
The Clinical Findings Useful for Driving Safety Advice for Parkinson's Disease Patients.
Intern Med 57: 1977-1982, 2018pubmed
Shinoda T, Nakashita S, Hamada M, Hirono K, Ito M, Miyagi T, Namihira Y, Tokashiki T, Kashihara K, Nakashima K, Maeda T
Egogram characteristics in Japanese patients with Parkinson's disease.
Neurology and Clinical Neuroscience 6: 71-76, 2018
Dawson BK, Fereshtehnejad SM, Anang JBM, Nomura T, Rios-Romenets S, Nakashima K, Gagnon JF, Postuma RB
Office-Based Screening for Dementia in Parkinson Disease: The Montreal Parkinson Risk of Dementia Scale in 4 Longitudinal Cohorts.
JAMA Neurol 75: 704-710, 2018pubmed
Tohnai G, Nakamura R, Sone J, Nakatochi M, Yokoi D, Katsuno M, Watanabe H, Watanabe H, Ito M, Li Y, Izumi Y, Morita M, Taniguchi A, Kano O, Oda M, Kuwabara S, Abe K, Aiba I, Okamoto K, Mizoguchi K, Hasegawa K, Aoki M, Hattori N, Onodera O, Naruse H, Mitsui J, Takahashi Y, Goto J, Ishiura H, Morishita S, Yoshimura J, Doi K, Tsuji S, Nakashima K, Kaji R, Atsuta N, Sobue G; Japanese Consortium for Amyotrophic Lateral Sclerosis Research (JaCALS).
Frequency and characteristics of the TBK1 gene variants in Japanese patients with sporadic amyotrophic lateral sclerosis.
Neurobiol Aging 64: 158, 2018pubmed
Watanabe Y, Matsuba T, Nakanishi M, Une M, Hanajima R, Nakashima K
Tetanus toxin fragments and Bcl-2 fusion proteins:cytoprotection and retrograde axonal migration.
BMC Biotechnol 18: 39, 2018pubmed
Moriyama Y, Yoshino A, Muramatsu T, Mimura M
Detailed analysis of the Japanese version of the Rapid Dementia Screening Test using Arabic-hiragana conversion.
Psychogeriatrics 18: 446-450, 2018pubmed
Komeda H, Eguchi Y, Kusumi T, Kato Y, Narumoto J, Mimura M
Decision-making based on social conventional rules by elderly people.
Front Psychol 9: 1412, 2018pubmed
Komatsu H, Yagasaki K, Kida H, Eguchi Y, Niimura H
Preparing for a Paradigm Shift in Aging Populations: Listen to the Oldest Old.
Int J Qual Stud Health Well-being 13: 1511768, 2018pubmed
Wake T, Tabuchi H, Funaki K, Ito D, Yamagata B, Yoshizaki T, Kameyama M, Nakahara T, Murakami K, Jinzaki M, Mimura M
The psychological impact of disclosing amyloid status to Japanese elderly: A preliminary study on asymptomatic patients with subjective cognitive decline.
Int Psychogeriatr 30: 635-639, 2018pubmed
Yuki-Nozaki S, Noguchi-Shinohara M, Domoto C, Ikeda Y, Samuraki M, Iwasa K, Yokogawa M, Asai K, Komai K, Nakamura H, Yamada M
Differences in dementia beliefs between non-demented public screeners and in-home screeners and their potential impact on future dementia screening intention: the Nakajima Study.
J Alzheimers Dis 62: 1651-1661, 2018pubmed
Noguchi-Shinohara M, Abe C, Yuki-Nozaki S, Domoto C, Mori A, Hayashi K, Shibata S, Ikeda Y, Sakai K, Iwasa K, Yokogawa M, Ishimiya M, Nakamura H, Yokoji H, Komai K, Nakamura H, Yamada M
Higher blood vitamin C levels are associated with reduction of apolipoprotein E E4-related risks of cognitive decline in women: the Nakajima Study.
J Alzheimers Dis 63: 1289-1297, 2018pubmed
Komatsu J, Matsunari I, Samuraki M, Shima K, Noguchi-Shinohara M, Sakai K, Hamaguchi K, Ono K, Matsuda H, Yamada M
Optimization of DARTEL settings for the detection of Alzheimer’s disease.
Am J Neuroradiol 39: 473-478, 2018pubmed
Ishimiya M, Nakamura H, Kobayashi Y, Noguchi-Shinohara M, Abe C, Dohmoto C, Ikeda Y, Tokuno K, Ooi K, Yokokawa M, Iwasa K, Komai K, Kawashiri S, Yamada M
Tooth loss-related dietary patterns and cognitive impairment in an elderly Japanese population: the Nakajima Study.
PLoS One 13: e0194504, 2018pubmed
Yuki-Nozaki S, Noguchi-Shinohara M, Domoto C, Ikeda Y, Samuraki M, Iwasa K, Yokogawa M, Asai K, Komai K, Nakamura H, Yamada M
Differences in dementia beliefs between non-demented public screeners and in-home screeners and their potential impact on future dementia screening intention: the Nakajima Study.
J Alzheimers Dis 62: 1651-1661, 2018pubmed
Goto S, Sasaki A, Takahashi I, Mitsuhashi Y, Nakaji S, Matsubara A
Relationship between cognitive function and balance in a community-dwelling population in Japan.
Acta Otolaryngol 138: 471-474, 2018pubmed
鈴木 航太、新村 秀人、三村 將
85歳以上の超高齢者における身体的健康とメンタルヘルス.
臨床精神医学 46: 1315-1325, 2017
喜田 恒、新村 秀人、三村 將
超高齢者における抑うつ、認知機能低下と老年的超越.
臨床精神医学 46: 1327-1333, 2017
Inui A, Takahashi I, Kurauchi S, Soma Y, Oyama T, Tamura Y, Noguchi T, Murashita K, Nakaji S, Kobayashi W
Oral conditions and dysphagia in Japanese, community-dwelling middle-and older-aged adults, independent in daily living.
Clin Interv Aging 12: 515-521, 2017pubmed
Chiba D, Wada K, Tanaka T, Kumagai G, Sasaki E, Takahashi I, Nakaji S, Ishibashi Y
Serum pentosidine concentration is associated with radiographic severity of lumbar spondylosis in a general Japanese population.
J Bone Miner Metab 35: 65-72, 2017pubmed
McKeith I, Boeve B, Dickson D, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard C, Bayston A, Beach T, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda J, El-Agnaf O, Feldman H, Ferman T, Ffytche D, Fujishiro H, Galasko D, Graff-Radford N, Goldman J, Gomperts S, Honing L, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee V, Leverenz J, Lippa C, Lewis S, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine T, Moreno E, Mori E, Murray M, O'Brien J, Orimo S, MD; Postuma R, Ramaswamy S, Ross O, Salmon D, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo J, Trojanowski J, Tsuang D, Walker Z, Yamada M, Kosaka K
Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.
Neurology 89: 88-100, 2017pubmed
Noguchi-Shinohara M, Komatsu J, Samuraki M, Matsunari I, Ikeda T, Sakai K, Hamaguchi T, Ono K, Nakamura H, Yamada M
Cerebral amyloid angiopathy-related microbleeds and CSF biomarkers in Alzheimer’s disease.
J Alzheimers Dis 55: 905-913, 2017pubmed
Yoshida K, Roberts R, Suzuki T, Lebowitz B, Reeves S, Howard R, Abe T, Mimura M, Uchida H
Lack of early improvement with antipsychotics is a marker for subsequent nonresponse in behavioral and psychological symptoms of dementia: Analysis of CATIE-AD Data.
Am J Geriatr Psychiatry 25: 708-716, 2017pubmed
Takechi S, Yoshimura K, Oguma Y, Saito Y, Mimura M
Relationship between social capital and cognitive functions among community-based elderly.
Advances in Alzheimer’s Disease 6: 45-51, 2017
Nagata T, Nakajima S, Shinagawa S, Plitman E, Nakayama K, Graff-Guerrero A, Mimura M
Baseline predictors of antipsychotic treatment continuation and response at week 8 in patients with Alzheimer's disease with psychosis or aggressive symptoms: An analysis of the CATIE-AD Study.
J Alzheimers Dis 60: 263-272, 2017pubmed
Liu YC, Meguro K, Nakamura K, Akanuma K, Nakatsuka M, Seki T, Nakaaki S, Mimura M, Kawakami N
Depression and dementia in old-old population: History of depression may be associated with dementia onset: The Tome Project.
Front Aging Neurosci 9: 335, 2017pubmed
Ozawa C, Roberts R, Yoshida K, Suzuki T, Lebowitz B, Reeves S, Howard R, Abe T, Mimura M, Uchida H
Placebo effects in the treatment of noncognitive symptoms of Alzheimer's disease: Analysis of the CATIE-AD Data.
J Clin Psychiatry 78: e1204-e1210, 2017pubmed
Hayashi R, Yamaguchi S, Narimatsu T, Miyata H, Katsumata Y, Mimura M
Statokinetic dissociation (Riddoch phenomenon) in a patient with homonymous hemianopsia as the first sign of posterior cortical atrophy.
Case Rep Neurol 9: 256–260, 2017pubmed
Sao T, Yoshino Y, Yamazaki K, Ozaki Y, Mori Y, Ochi S, Yoshida T, Mori T, Iga JI, Ueno SI
MEF2C mRNA expression and cognitive function in Japanese patients with Alzheimer's disease.
Psychiatry Clin Neurosci 72: 160-167, 2018. Epub 2017 Dec 1.pubmed
Mise A, Yoshino Y, Yamazaki K, Ozaki Y, Sao T, Yoshida T, Mori T, Mori Y, Ochi S, Iga JI, Ueno SI
TOMM40 and APOE Gene Expression and Cognitive Decline in Japanese Alzheimer's Disease Subjects.
J Alzheimers Dis 60: 1107-1117, 2017pubmed
Yoshino Y, Mori T, Yoshida T, Toyota Y, Shimizu H, Iga JI, Nishitani S, Ueno SI
Improvement of Visuo-spatial Function Assessed by Raven's Colored Progressive Matrices in Dementia with Lewy Bodies by Donepezil Treatment.
Clin Psychopharmacol Neurosci 15: 243-247, 2017pubmed
Yoshino Y, Yamazaki K, Ozaki Y, Sao T, Yoshida T, Mori T, Mori Y, Ochi S, Iga JI, Ueno SI
INPP5D mRNA Expression and Cognitive Decline in Japanese Alzheimer's Disease Subjects.
J Alzheimers Dis 58: 687-694, 2017pubmed
Ozaki Y, Yoshino Y, Yamazaki K, Sao T, Mori Y, Ochi S, Yoshida T, Mori T, Iga JI, Ueno SI
DNA methylation changes at TREM2 intron 1 and TREM2 mRNA expression in patients with Alzheimer's disease.
J Psychiatr Res 92: 74-80, 2017 pubmed
Yamamoto M, Wada-Isoe K, Yamashita F, Nakashita S, Kishi M, Tanaka K, Yamawaki M, Nakashima K
Association between exercise habits and subcortical gray matter volumes in healthy elderly people: A population-based study in Japan.
eNeurologicalSci 7: 1-6, 2017 pubmed
Mukai N, Ohara T, Hata J, Hirakawa Y, Yoshida D, Kishimoto H, Koga M, Nakamura U, Kitazono T, Kiyohara Y, Ninomiya T
Alternative measures of hyperglycemia and risk of alzheimer's disease in the community: the Hisayama Study.
J Clin Endocrinol Metab 102: 3002-3010, 2017pubmed
Umehara K, Mukai N, Hata J, Hirakawa Y, Ohara T, Yoshida D, Kishimoto H, Kitazono T, Hoka S, Kiyohara Y, Ninomiya T
Association between serum vitamin D and all-cause and cause-specific death in a general Japanese population - the Hisayama Study -.
Circ J 81: 1315-1321, 2017pubmed
Hata J, Fukuhara M, Sakata S, Arima H, Hirakawa Y, Yonemoto K, Mukai N, Kitazono T, Kiyohara Y, Ninomiya T
White-coat and masked hypertension are associated with albuminuria in a general population: the Hisayama Study.
Hypertens Res 40: 937-943, 2017pubmed
Takeuchi K, Ohara T, Furuta M, Takeshita T, Shibata Y, Hata J, Yoshida D, Yamashita Y, Ninomiya T
Tooth loss and risk of dementia in the community: the Hisayama Study.
J Am Geriatr Soc 65: e95-e100, 2017 pubmed
Oishi E, Ohara T, Sakata S, Fukuhara M, Hata J, Yoshida D, Shibata M, Ohtsubo T, Kitazono T, Kiyohara Y, Ninomiya T
Day-to-day blood pressure variability and risk of dementia in a general Japanese elderly population: the Hisayama Study.
Circulation 136: 516-525, 2017pubmed
Ohara T, Hata J, Yoshida D, Mukai N, Nagata M, Iwaki T, Kitazono T, Kanba S, Kiyohara Y, Ninomiya T
Trends in dementia prevalence, incidence, and survival rate in a Japanese community.
Neurology 88: 1925-1932, 2017pubmed
Usui T, Nagata M, Hata J, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Kitazono T, Kiyohara Y, Ninomiya T
Serum non-high-density lipoprotein cholesterol and risk of cardiovascular disease in community dwellers with chronic kidney disease: the Hisayama Study.
J Atheroscler Thromb 24: 706-715, 2017. Epub 2016 Nov 12.pubmed
Takae K, Nagata M, Hata J, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Tsuruya K, Kitazono T, Kiyohara Y, Ninomiya T
Serum uric acid as a risk factor for chronic kidney disease in a Japanese community - the Hisayama Study -.
Circ J 80: 1857-1862, 2016pubmed
Hata J, Mukai N, Nagata M, Ohara T, Yoshida D, Kishimoto H, Shibata M, Hirakawa Y, Endo M, Ago T, Kitazono T, Oike Y, Kiyohara Y, Ninomiya T
Serum angiopoietin-like protein 2 is a novel risk factor for cardiovascular disease in the community: the Hisayama Study.
Arterioscler Thromb Vasc Biol 36: 1686-1691, 2016pubmed
Kishimoto H, Ohara T, Hata J, Ninomiya T, Yoshida D, Mukai N, Nagata M, Ikeda F, Fukuhara M, Kumagai S, Kanba S, Kitazono T, Kiyohara Y
The long-term association between physical activity and risk of dementia in the community: the Hisayama Study.
Eur J Epidemiol 31: 267-274, 2016pubmed
Nakashita S, Wada-Isoe K, Uemura Y, Tanaka K, Yamamoto M, Yamawaki M, Nakashima K
Clinical assessment and prevalence of parkinsonism in Japanese elderly people.
Acta Neurol Scand 133: 373-379, 2016pubmed
Yoshino Y, Mori T, Yoshida T, Yamazaki K, Ozaki Y, Sao T, Funahashi Y, Iga JI, Ueno SI
Elevated mRNA Expression and Low Methylation of SNCA in Japanese Alzheimer's Disease Subjects.
J Alzheimers Dis 54: 1349-1357, 2016pubmed
Yamazaki K, Yoshino Y, Mori T, Okita M, Yoshida T, Mori Y, Ozaki Y, Sao T, Iga J, Ueno S
Association Study and Meta-Analysis of Polymorphisms, Methylation Profiles, and Peripheral mRNA Expression of the Serotonin Transporter Gene in Patients with Alzheimer's Disease.
Dement Geriatr Cogn Disord 41: 334-347, 2016pubmed
Kazui H, Yoshiyama K, Kanemoto H, Suzuki Y, Sato S, Hashimoto M, Ikeda M, Tanaka H, Hatada Y, Matsushita M, Nishio Y, Mori E, Tanimukai S, Komori K, Yoshida T, Shimizu H, Matsumoto T, Mori T, Kashibayashi T, Yokoyama K, Shimomura T, Kabeshita Y, Adachi H, Tanaka T
Differences of Behavioral and Psychological Symptoms of Dementia in Disease Severity in Four Major Dementias.
PLoS One 11: e0161092, 2016pubmed
Yoshida T, Mori T, Shimizu H, Yoshino Y, Sonobe N, Matsumoto T, Kikuchi K, Miyagawa M, Iga J, Mochizuki T, Ueno SI.
Neural basis of visual perception and reasoning ability in Alzheimer's disease: correlation between Raven's Colored Progressive Matrices test and 123 I-IMP SPECT imaging results.
Int J Geriatr Psychiatry 32: 407-413, 2017. Epub 2016 Apr 19.pubmed
Funahashi Y, Yoshino Y, Yamazaki K, Mori Y, Mori T, Ozaki Y, Sao T, Ochi S, Iga JI, Ueno SI.
DNA methylation changes at SNCA intron 1 in patients with dementia with Lewy bodies.
Psychiatry Clin Neurosci 71: 28-35, 2017. Epub 2016 Nov 3.pubmed
Nagata T, Nakajima S, Shinagawa S, Plitman E, Graff-Guerrero A, Mimura M, Nakayama K
Psychosocial or clinico-demographic factors related to neuropsychiatric symptoms in patients with Alzheimer's disease needing interventional treatment: Analysis of the CATIE-AD study.
Int J Geriatr Psychiatry 32: 1264-1271, 2017. Epub 2016 Oct 7.pubmed
Takao M, Hirose N, Arai Y, Mihara B, Mimura M
Neuropathology of supercentenarians - Four autopsy case studies.
Acta Neuropathol Commun 4: 97, 2016pubmed
Moriyama Y, Yoshino A, Muramatsu T, Mimura M
Detailed analysis of error patterns in the number-transcoding task on the Japanese version of the Rapid Dementia Screening Test.
Psychogeriatrics 17: 164-169, 2017. Epub 2016 Jun 27.pubmed
Moriyama Y, Yoshino A, Muramatsu T, Mimura M
Detailed analysis of the supermarket task included on the Japanese version of the Rapid Dementia Screening Test.
Psychogeriatrics 17: 170-176, 2017. Epub 2016 Jun 30.pubmed
Yagi T, Ito D, Sugiyama D, Iwasawa S, Tabuchi T, Konishi M, Araki M, Saitoh N, Nihei Y, Mimura M, Suzuki N
Diagnostic accuracy of neuropsychological tests for classification of dementia.
Neurology Asia 21: 47–54, 2016
Nagata T, Shinagawa S, Nakajima S, Plitman E, Mihashi Y, Hayashi S, Mimura M, Nakayama K
Classification of neuropsychiatric symptoms requiring antipsychotic treatment in patients with Alzheimer's disease: Analysis of the CATIE-AD Study.
J Alzheimers Dis 50: 839-845, 2016pubmed
Kawasaki M, Arai Y, Takayama M, Hirata T, Takayama M, Abe Y, Niimura H, Mimura M, Takebayashi T, Hirose N
Carotid atherosclerosis, cytomegalovirus infection, and cognitive decline in the very old: a community-based prospective cohort study.
Age 38: 29, 2016pubmed
Moriyama Y, Yoshino A, Yamanaka K, Kato M, Muramatsu T, Mimura M
The Japanese version of the Rapid Dementia Screening Test is effective compared to the clock-drawing test for detecting patients with mild Alzheimer's disease.
Psychogeriatrics 16: 233-239, 2016pubmed
Watanabe-Nakayama T, Ono K, Itami M, Takahashi R, Teplow DB, Yamada M
High-speed atomic force microscopy reveals structural dynamics of amyloid β1-42 aggregates.
Proc Natl Acad Sci USA 113: 5835-5840, 2016pubmed
Umeda T, Ono K, Sakai A, Yamashita M, Mizuguchi M, Klein WL, Yamada M, Mori H, Tomiyama T
Rifampicin is a candidate preventive medicine against amyloid β and tau oligomers.
Brain 139: 1568-1586, 2016pubmed
Inui A, Takahashi I, Sawada K, Naoki A, Oyama T, Tamura Y, Osanai T, Satake A, Nakaji S, Kobayashi W
Teeth and physical fitness in a community-dwelling 40 to 79-year-old Japanese population.
Clin Interv Aging 11: 873-878, 2016pubmed
Chiba D, Tsuda E, Maeda S, Sasaki E, Takahashi I, Nakaji S, Ishibashi Y
Evaluation of a quantitative measurement of suprapatellar effusion by ultrasonography and its association with symptoms of radiographic knee osteoarthritis: a cross-sectional observational study.
Arthritis Res Ther 18: 181, 2016pubmed
Yamauchi R, Inoue R, Chiba D, Yamamoto Y, Harada Y, Takahashi I, Nakaji S, Ishibashi Y
Association of clinical and radiographic signs of femoroacetabular impingement in the general population.
J Orthop Sci 22: 94-98, 2017. Epub 2016 Nov 4.pubmed